Example scenario P1

Attempt to reproduce the CYP2C9*1*3 case reported in [Thijssen & al., 2001]. After loading, a variety of regimens were administered until a stable INR between 2 and 3 was obtained with 5mg of acenocoumarol/week. We could obtain a similar behaviour with a CYP2C9 activity of 0.1 that of *1*1 and a simulated subject weight of 62kg (as in the reported case).

Click on `Simulate!' below and wait about 15 seconds to see the results, which are documented here.

Patient weight (kg): CYP2C9 activity

DrugDayHourMinDose   DrugDayHourMinDose